Endocrine Abstracts

Gestational diabetes mellitus (GDM) is a common condition affecting 2–10% of pregnant women in the USA and in Europe and is associated with adverse outcomes for both the fetus and the mother. Previous GDM is a major risk factor for type 2 diabetes (T2DM), which occurs in 20–60% of affected women within 5 years of the pregnancy1. In studies comparing women with GDM with those with unaffected pregnancies, relative risks for the development of diabetes after ...

Acromegaly is amongst other symptoms associated with myopathy, alterations of energy expenditure and insulin action which are mediated by growth hormone (GH) and insulin-like growth factors (IGFs). It is unclear to which extent these abnormalities remain after treatment. Thus, we examined glucose metabolism, intracellular fat deposition and mitochondrial function in patients with prior acromegaly (AM).Six AM (4f/2 m, age: 49±10 years, body mass inde...